Clacef 250 mg Tablet is a combination antibiotic medication containing 250 mg of cefuroxime axetil and 62.5 mg of clavulanic acid. Cefuroxime is a second-generation cephalosporin that inhibits bacterial cell wall synthesis, leading to bacterial cell death. Clavulanic acid is a beta-lactamase inhibitor that protects cefuroxime from degradation by beta-lactamase enzymes produced by certain bacteria. This combination enhances the effectiveness of cefuroxime against a broader spectrum of bacteria, including those resistant to beta-lactam antibiotics. Clacef 250 mg Tablet is used to treat various bacterial infections, including pharyngitis, tonsillitis, acute bacterial maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, secondary bacterial infections of acute bronchitis, uncomplicated skin and skin structure infections, uncomplicated urinary tract infections, uncomplicated gonorrhoea, community-acquired pneumonia, multidrug-resistant typhoid fever, and early Lyme disease. The typical adult dosage is 250 mg twice daily for 5 to 10 days, depending on the specific infection being treated. It is important to complete the full course of therapy as prescribed to prevent the development of antibiotic-resistant bacteria. Clacef 250 mg Tablet is manufactured by Opso Saline Ltd. and is available in Bangladesh