• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
VASTAREL MR 35 MG is indicated for the treatment of angina pectoris (chest pain) associated with coronary artery disease. It works by improving the efficiency of the heart muscle, increasing its ability to utilize oxygen, and enhancing blood flow to the heart. Trimetazidine, the active ingredient, reduces the frequency and severity of angina attacks by improving myocardial metabolism. It is often used as an adjunct to other heart medications for the management of angina.

Pharmacology:
VASTAREL MR 35 MG contains Trimetazidine, a metabolic agent that works by enhancing the metabolism of heart cells, specifically under conditions of limited oxygen supply (ischemia). Trimetazidine helps the heart muscle use glucose more efficiently, thus reducing the reliance on fatty acids, which require more oxygen to metabolize. This improves energy production and prevents the buildup of toxic metabolic byproducts. As a result, VASTAREL MR 35 MG helps maintain heart function, especially during periods of stress or oxygen deprivation, such as in angina.

Dosage:

• The usual recommended dose for adults is 35 mg once or twice daily, depending on the doctor’s instructions.

• The maximum recommended dose is 70 mg per day.

• Always follow your healthcare provider's instructions regarding the dose and frequency of administration.

Administration:
Take VASTAREL MR 35 MG orally with a glass of water. It is best taken with food to minimize stomach irritation. Do not crush, chew, or break the tablet, as this may affect the modified-release formulation. Taking it at the same time each day will help maintain consistent blood levels of the medication.

Interaction:
VASTAREL MR 35 MG may interact with other medications, including:

• Antihypertensive medications (e.g., beta-blockers or ACE inhibitors), which may increase the risk of low blood pressure (hypotension).

• CYP3A4 inhibitors may affect the metabolism of Trimetazidine.

• Other cardiovascular medications may affect the overall effectiveness of VASTAREL MR 35 MG.
  Always inform your doctor about all medications you are currently taking, including over-the-counter medicines and herbal supplements.

Contraindications:
VASTAREL MR 35 MG is contraindicated in individuals who:

• Are allergic to Trimetazidine or any of its ingredients.

• Have severe renal impairment (kidney dysfunction).

• Have a history of Parkinson's disease or restless leg syndrome as it may worsen symptoms.

• Are pregnant or breastfeeding.

• Are under 18 years of age (safety and effectiveness in children have not been established).

Side Effects:
Common side effects of VASTAREL MR 35 MG may include:

• Headache, dizziness, or lightheadedness.

• Nausea, vomiting, or abdominal discomfort.

• Fatigue or feeling generally unwell.
  Less common but serious side effects can include:

• Movement disorders such as tremors, stiffness, or difficulty walking, which may indicate a neurological issue.

• Allergic reactions such as rash, itching, or swelling.
  If you experience any unusual or severe side effects, such as tremors or sudden difficulty walking, consult your doctor immediately.

Pregnancy & Lactation:
Pregnancy:
VASTAREL MR 35 MG should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Consult your doctor if you are pregnant or planning to become pregnant.
Lactation:
Trimetazidine may pass into breast milk, so it is not recommended for use during breastfeeding. Consult your healthcare provider before using VASTAREL MR 35 MG while breastfeeding.

Therapeutic Class:
Metabolic Agents (Anti-anginal drug).

Storage Conditions:
Store VASTAREL MR 35 MG at room temperature, away from moisture, heat, and direct sunlight.
Keep the medication tightly closed in its original container.
Keep out of the reach of children.
Do not use the medication after the expiration date printed on the packaging.