Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Metro is indicated for:
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Treatment of anaerobic bacterial infections (e.g., intra-abdominal infections, skin and soft tissue infections)
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Protozoal infections such as amoebiasis, giardiasis, and trichomoniasis
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Bacterial vaginosis and pelvic inflammatory disease
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Used in combination with other antibiotics for Helicobacter pylori eradication
Pharmacology:
Metronidazole acts by entering the anaerobic microorganism and disrupting its DNA, leading to cell death. It is effective against obligate anaerobic bacteria and certain protozoa.
Dosage & Administration:
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Typical adult dose: 400 mg orally every 8 to 12 hours depending on infection severity
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Should be taken with food or milk to reduce gastrointestinal irritation
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Complete the full prescribed course even if symptoms improve
Interaction:
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Avoid alcohol during treatment and for at least 48 hours after (disulfiram-like reaction)
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May increase effects of warfarin and lithium
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Interaction with phenobarbital and phenytoin may reduce metronidazole levels
Contraindications:
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Hypersensitivity to metronidazole or other nitroimidazole derivatives
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First trimester of pregnancy (use only if clearly necessary)
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Use cautiously in patients with CNS disorders
Side Effects:
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Common: Nausea, metallic taste, headache, dizziness, abdominal pain
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Rare: Seizures, peripheral neuropathy, hypersensitivity reactions, dark urine
Pregnancy & Lactation:
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Use only if benefits outweigh risks in pregnancy, especially after the first trimester
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Metronidazole is excreted in breast milk; caution advised during breastfeeding
Precautions & Warnings:
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Monitor for signs of peripheral neuropathy and CNS effects
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Avoid alcohol to prevent adverse reactions
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Caution in patients with liver impairment
Therapeutic Class:
Nitroimidazole antibiotic and antiprotozoal agent
Storage Conditions:
Store below 30°C in a dry place away from direct sunlight and moisture. Keep out of reach of children.
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