• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।

Indications:
Indicated for the treatment of type 2 diabetes mellitus, especially in overweight patients, when diet and exercise alone do not result in adequate glycemic control.

Pharmacology:
Metformin decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.

Dosage:
Initially 500 mg once or twice daily with meals. Maximum dose: 2000–2550 mg/day in divided doses depending on response and tolerability.

Administration:
Should be taken with meals to reduce gastrointestinal side effects. Do not crush or chew the tablet unless specified as extended-release.

Interaction:
May interact with alcohol, iodinated contrast agents, corticosteroids, beta-blockers, and diuretics. Concomitant use may increase the risk of lactic acidosis or reduce glucose-lowering effect.

Contraindications:
Renal dysfunction, metabolic acidosis, diabetic ketoacidosis, severe liver disease, hypersensitivity to Metformin.

Side Effects:
Common side effects include nausea, vomiting, diarrhea, abdominal discomfort, and metallic taste. Rare but serious side effect: lactic acidosis.

Pregnancy & Lactation:
Generally safe during pregnancy, but insulin may be preferred. Small amounts pass into breast milk; use with caution during lactation.

Precautions & Warnings:
Monitor renal function before and during treatment. Avoid in patients at risk of lactic acidosis. Use with caution in elderly and dehydrated patients.

Therapeutic Class:
Biguanide-type oral antidiabetic agents

Storage Conditions:
Store below 30°C in a dry place. Keep away from direct sunlight and moisture. Keep out of reach of children.