রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*

Indications:

• Anxiety disorders

• Insomnia (short-term)

• Muscle spasms

• Seizure disorders (as adjunct therapy)

• Alcohol withdrawal symptoms

• Preoperative sedation

Pharmacology:
Diazepam is a benzodiazepine that enhances the effect of the neurotransmitter GABA (gamma-aminobutyric acid) in the brain. This leads to calming effects, muscle relaxation, anticonvulsant activity, and sedation.

Dosage:

• Adults: 2 to 10 mg, 2 to 4 times daily based on the condition

• Elderly or debilitated: Lower initial doses

• Must be individualized and prescribed by a physician

Administration:

• Oral administration

• Should be taken with water

• Preferably at bedtime for insomnia or at fixed times for anxiety

• Do not abruptly discontinue without medical advice

Interaction:

• Increased CNS depression with alcohol, opioids, antihistamines, antidepressants

• May increase plasma levels of phenytoin

• Interaction with cimetidine, fluoxetine, and other CYP450 inhibitors

Contraindications:

• Hypersensitivity to Diazepam or other benzodiazepines

• Severe respiratory insufficiency

• Myasthenia gravis

• Sleep apnea syndrome

• Acute narrow-angle glaucoma

Side Effects:

• Drowsiness, dizziness, fatigue

• Muscle weakness, impaired coordination

• Confusion (especially in elderly)

• Risk of dependence or withdrawal symptoms with long-term use

Pregnancy & Lactation:

• Not recommended during pregnancy (especially first trimester)

• Can cause neonatal withdrawal symptoms if used in late pregnancy

• Excreted in breast milk — use with caution during lactation

Precautions & Warnings:

• Use cautiously in patients with liver/kidney impairment, elderly, or those with a history of substance abuse

• Avoid alcohol and operating machinery

• Gradual dose reduction recommended to avoid withdrawal

Therapeutic Class:

• Benzodiazepines, Anxiolytics, Sedatives, Anticonvulsants

Storage Conditions:

• Store below 25°C in a dry place

• Protect from light and moisture

• Keep out of reach of children