Indications:
Betadine 10% Solution is indicated for the prevention and treatment of infections in minor wounds, cuts, burns, abrasions, and ulcers. It is also used for preoperative skin disinfection and as a surgical scrub.

Pharmacology:
The active ingredient, povidone-iodine, releases iodine upon application, which penetrates microbial cell walls, leading to cell death. It is effective against a broad spectrum of pathogens, including bacteria, viruses, fungi, and protozoa. 

Dosage:

• Topical Application: Apply directly to the affected area 1 to 3 times daily.

• Gargle/Mouthwash: Use 10 ml diluted with an equal volume of warm water, gargle for 30 seconds, up to 4 times daily. 

Administration:
Clean the affected area and apply Betadine 10% Solution directly. Do not dilute unless directed. For mouthwash, dilute as instructed and avoid swallowing.

Interaction:
Avoid concurrent use with other antiseptics or enzymatic wound agents, as interactions may reduce efficacy.

Contraindications:

• Known hypersensitivity to iodine or povidone-iodine.

• Patients with thyroid disorders, especially hyperthyroidism.

• Not recommended for use in neonates or during pregnancy without medical advice. 

Side Effects:
Possible side effects include local skin irritation, redness, itching, or burning sensation. Prolonged use over large areas may affect thyroid function. 

Pregnancy & Lactation:
Use with caution during pregnancy and lactation. Consult a healthcare professional before use.

Precautions & Warnings:

• For external use only.

• Avoid contact with eyes and mucous membranes.

• Do not use on large or deep wounds without medical supervision.

Therapeutic Class:
Topical Antiseptic/Disinfectant

Storage Conditions:
Store below 25°C in a cool, dry place, away from direct sunlight. Keep out of reach of children.