রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications

Indicated for the management of moderate to moderately severe pain when treatment with either Paracetamol or Tramadol alone is inadequate.

Pharmacology

This product combines two analgesics:

• Paracetamol: A non-opioid analgesic and antipyretic that works by inhibiting prostaglandin synthesis.

• Tramadol: A centrally acting synthetic opioid analgesic that binds to µ-opioid receptors and inhibits norepinephrine and serotonin reuptake.

Dosage

The usual adult dose is 1–2 tablets every 4 to 6 hours as needed, not exceeding 8 tablets in 24 hours. Dosage should be individualized based on patient need and response.

Administration

To be taken orally with or without food. The tablet should be swallowed whole, not broken or chewed.

Interaction

Caution when used with CNS depressants, MAO inhibitors, SSRIs, tricyclic antidepressants, or other drugs that lower the seizure threshold.

Contraindications

Hypersensitivity to Paracetamol, Tramadol, or any component of the product. Contraindicated in cases of acute alcohol intoxication, uncontrolled epilepsy, or severe respiratory depression.

Side Effects

Common: Nausea, dizziness, constipation, drowsiness, headache.
Serious: Respiratory depression, seizures, serotonin syndrome, liver toxicity (from high doses of Paracetamol).

Pregnancy & Lactation

Should be used during pregnancy only if clearly needed. Tramadol is excreted in breast milk; not recommended during breastfeeding. Paracetamol is generally considered safe but consult physician.

Precautions & Warnings

Monitor for signs of misuse, abuse, or addiction. Use with caution in patients with hepatic or renal impairment. Long-term use may lead to dependency or liver damage.

Therapeutic Class

Combined Analgesics (Opioid and Non-opioid)

Storage Conditions

Store below 30°C, away from light and moisture. Keep out of reach of children.