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RABE 20 MG Capsule

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Out Of Stock

Product Code : 101910122400601

Short Description

RABE 20 MG contains Rabeprazole, a proton pump inhibitor used to treat acid-related stomach disorders.

Name Brand Generic Name Strength PPF Price
RABE 20 MG Capsule ARISTOPHARMA LTD RABEPRAZOLE 20mg capsule 8
৳ 8
Qty :

Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:
RABE 20 MG is indicated for the treatment of:

  • Gastroesophageal reflux disease (GERD)

  • Duodenal and gastric ulcers

  • Zollinger-Ellison syndrome

  • Erosive esophagitis

  • Maintenance therapy after healing of erosive esophagitis

  • Helicobacter pylori eradication (in combination with antibiotics)

Pharmacology:
Rabeprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by inhibiting the H⁺/K⁺ ATPase enzyme system at the secretory surface of the gastric parietal cells. This reduces both basal and stimulated acid production, aiding in healing and symptom relief.

Dosage & Administration:

  • GERD: 20 mg once daily for 4–8 weeks

  • Gastric ulcer: 20 mg once daily for 4–6 weeks

  • Duodenal ulcer: 20 mg once daily for 4 weeks

  • H. pylori eradication: 20 mg twice daily with antibiotics for 7–10 days

  • Should be taken before meals, preferably in the morning

  • Swallow whole; do not crush or chew

Interaction:

  • May reduce absorption of drugs dependent on gastric pH (e.g., ketoconazole, atazanavir)

  • May increase levels of digoxin, cyclosporine, and warfarin

  • Use with caution with methotrexate—can delay clearance

  • Antacids can be co-administered without affecting efficacy

Contraindications:

  • Hypersensitivity to Rabeprazole or substituted benzimidazoles

  • Severe hepatic impairment without medical supervision

  • Concomitant use with rilpivirine-containing products

Side Effects:

  • Headache, nausea, diarrhea, abdominal pain

  • Flatulence, constipation

  • Long-term use may lead to vitamin B12 deficiency, hypomagnesemia, or osteoporosis-related fractures

  • Rare: Skin rash, liver enzyme abnormalities

Pregnancy & Lactation:
Use only if clearly needed during pregnancy. Animal studies have not shown harm, but human data is limited. Rabeprazole is excreted in breast milk—use caution while breastfeeding.

Precautions & Warnings:

  • Prolonged use may increase risk of gastric malignancy

  • Monitor magnesium levels with long-term use

  • Evaluate for H. pylori infection in recurrent ulcers

  • Consider dose adjustment in hepatic impairment

Therapeutic Class:
Proton Pump Inhibitors (PPIs)

Storage Conditions:
Store below 30°C in a dry place, away from direct light and moisture. Keep out of reach of children.