Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
RUPA 10 MG is indicated for:
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Essential hypertension
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Chronic stable angina
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Vasospastic (Prinzmetal's) angina
Pharmacology:
Amlodipine is a dihydropyridine calcium channel blocker that inhibits calcium ion influx into vascular smooth muscle and cardiac muscle. This results in vasodilation, reduced peripheral vascular resistance, and improved myocardial oxygen delivery.
Dosage & Administration:
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Adults: 5–10 mg once daily, adjusted according to patient response.
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Can be taken with or without food.
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Should be taken regularly for effective control.
Interaction:
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May increase plasma concentrations with CYP3A4 inhibitors (e.g., diltiazem, ketoconazole).
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May enhance the effects of other antihypertensives.
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Caution with simvastatin (dose adjustment may be needed).
Contraindications:
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Hypersensitivity to Amlodipine or other dihydropyridines
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Severe hypotension
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Cardiogenic shock
Side Effects:
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Common: headache, dizziness, peripheral edema, flushing
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Rare: palpitations, fatigue, nausea
Pregnancy & Lactation:
Use only if clearly needed and under medical supervision. Safety in pregnancy and lactation is not well established.
Precautions & Warnings:
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Monitor blood pressure regularly
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Use cautiously in patients with severe aortic stenosis or heart failure
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Avoid sudden discontinuation
Therapeutic Class:
Calcium channel blockers (Dihydropyridines)
Storage Conditions:
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
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