Linzela 290 mcg is a medication that contains Linaclotide as its active ingredient. It is primarily used to treat Irritable Bowel Syndrome with Constipation (IBS-C) and Chronic Idiopathic Constipation (CIC). Linaclotide works by increasing the secretion of fluids in the intestines, which helps to soften stool and promote regular bowel movements. By stimulating the secretion of chloride and bicarbonate into the intestinal lumen, Linzela improves bowel transit and alleviates symptoms like abdominal pain and bloating. It is typically prescribed to individuals who have not responded well to other treatments for constipation and is usually taken once daily.