PASE 1 mg Tablet

PASE 1 mg Tablet

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Product Code : 116819615601902

Short Description Benzodiazepine for panic disorder, anxiety, and seizure control.

Name	Brand	Generic Name	Strength	PPF	Price
PASE 1 mg Tablet	Opsonin Pharma Ltd.	CLONAZEPAM	1 mg	TABLET	9

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Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:
• Panic disorder with or without agoraphobia
• Lennox‑Gastaut syndrome (petit mal variant), akinetic and myoclonic seizures
• Absence seizures in patients unresponsive to succinimides

Pharmacology:
Clonazepam enhances GABAergic neurotransmission via positive allosteric modulation of GABAₐ receptors, exhibiting anticonvulsant, anxiolytic, sedative, and muscle‑relaxant activity

Dosage:

Seizure disorders (adults): start ≤ 1.5 mg/day in 3 divided doses; increase by 0.5–1 mg every 3 days up to a max of 20 mg/day.
Panic disorder: start at 0.25 mg twice daily, titrate to 1 mg/day after 3 days
Pediatrics: 0.01–0.03 mg/kg/day (max 0.05 mg/kg/day) in divided doses

Administration:
Taken orally, with or without food; swallow whole. IV/IM forms available for status epilepticus in hospital settings .

Interaction:

CNS depressants and alcohol increase sedative effects.
Combining with other anticonvulsants may potentiate depressant actions

Contraindications:
Hypersensitivity to benzodiazepines, acute narrow‑angle glaucoma, severe liver disease. Use caution in open‑angle glaucoma with appropriate treatment

Side Effects:
Common: somnolence (≈37%), ataxia (5–10%), dizziness, fatigue, memory impairment, confusion, depression, blurred coordination .
Rare: respiratory depression (esp. in children), blood dyscrasias

Pregnancy & Lactation:
Risk of teratogenicity in pregnancy; use only if benefits outweigh risks. May pass into breast milk; caution advised

Precautions & Warnings:

High habit‑forming potential; avoid abrupt discontinuation due to risk of withdrawal symptoms (e.g., tremor, anxiety, confusion).
Taper dose gradually.
Caution in hepatic/renal impairment; avoid driving until response is known.
Monitor patients on multiple CNS depressants

Therapeutic Class:
Benzodiazepine (anticonvulsant, anxiolytic, hypnotic) .

Storage Conditions:
Store in a dry, cool place (<30 °C), protected from light. Keep out of reach of children