• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Microgest is indicated for:
Luteal phase support during assisted reproduction techniques (e.g., IVF)
Threatened or recurrent miscarriage due to progesterone deficiency
Secondary amenorrhea
Premenstrual syndrome (PMS)
Hormone replacement therapy (HRT) in postmenopausal women (combined with estrogen)
Dysfunctional uterine bleeding
Pharmacology:
Micronized progesterone is a naturally occurring hormone that prepares the endometrium for implantation and maintains early pregnancy. It transforms the proliferative endometrium into the secretory phase and modulates estrogen activity. Micronization enhances its absorption and bioavailability when administered orally or vaginally.
Dosage & Administration:
Oral/Vaginal: 200–400 mg daily depending on indication
Luteal support: 200 mg daily or as directed by physician
HRT: 200 mg daily for 12–14 days of a 28-day cycle
Administered orally, vaginally, or rectally as per physician’s advice
Take at the same time daily; bedtime dosing reduces sedation side effect
Interaction:
May alter effects of anticoagulants, antidiabetics
Enzyme inducers (e.g., rifampin, phenytoin) may reduce progesterone efficacy
Caution with other hormone therapies
Contraindications:
Undiagnosed vaginal bleeding
Known or suspected breast or genital cancer
History of thrombophlebitis or thromboembolic disorders
Liver dysfunction or disease
Hypersensitivity to progesterone or excipients
Side Effects:
Common: Drowsiness, bloating, breast tenderness, headache
Less common: Nausea, mood swings, abdominal pain
Serious: Thromboembolism, depression, jaundice (rare)
Pregnancy & Lactation:
Safe during early pregnancy for progesterone support. Use under medical supervision during breastfeeding.
Precautions & Warnings:
Monitor for thromboembolic events in high-risk patients
May cause sedation—avoid driving or machinery operation after intake
Regular medical follow-up required for long-term use
Not suitable for contraceptive purposes
Therapeutic Class:
Natural progesterone (Micronized) – Hormone Replacement / Luteal Support
Storage Conditions:
Store below 25°C in a dry place, away from light and moisture. Do not refrigerate. Keep out of reach of children.