Supadopa TR 145 mg is an extended-release combination medication containing 145 mg of Levodopa and 36.25 mg of Carbidopa. Levodopa is a precursor to dopamine, a neurotransmitter deficient in individuals with Parkinson's disease, while Carbidopa inhibits the breakdown of Levodopa outside the brain, ensuring more Levodopa reaches the brain and reducing side effects like nausea. This formulation provides a controlled release of the active ingredients, offering sustained symptom relief throughout the day.