Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
Abetis 10 mg is indicated for:
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Type 2 diabetes mellitus (non-insulin-dependent diabetes)
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As monotherapy or in combination with other oral antidiabetic agents or insulin, when diet and exercise alone are not sufficient
Pharmacology:
Glipizide is a second-generation sulfonylurea that lowers blood glucose by stimulating insulin release from pancreatic beta cells. It may also enhance peripheral insulin sensitivity over time. It is rapidly absorbed and has a relatively short duration of action.
Dosage:
As prescribed by a registered physician.
Typical initial dose: 2.5–5 mg daily, taken before breakfast.
Maximum daily dose: 40 mg in divided doses.
Administration:
Take orally 30 minutes before a meal. Swallow whole with water. Regular meal schedule is important to avoid hypoglycemia.
Interaction:
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Increased hypoglycemic effect with alcohol, beta-blockers, NSAIDs, and other antidiabetics
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Decreased effect with corticosteroids, diuretics, and thyroid hormones
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May mask signs of low blood sugar when taken with beta-blockers
Contraindications:
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Type 1 diabetes mellitus
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Diabetic ketoacidosis
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Severe liver or kidney impairment
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Hypersensitivity to Glipizide or sulfonylureas
Side Effects:
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Common: Hypoglycemia, nausea, headache, dizziness
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Less common: Allergic skin reactions, gastrointestinal discomfort
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Rare: Hepatic dysfunction, blood disorders (e.g., leukopenia)
Pregnancy & Lactation:
Not recommended during pregnancy. Insulin is preferred. Avoid use while breastfeeding unless specifically advised by a doctor.
Precautions & Warnings:
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Risk of hypoglycemia increases with missed meals or overdose
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Use cautiously in elderly, malnourished, or renal/hepatic-impaired patients
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Monitor blood glucose and HbA1c regularly
Therapeutic Class:
Sulfonylureas
Storage Conditions:
Store in a cool, dry place below 25°C. Protect from light and moisture. Keep out of reach of children.
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