Covista 50 is a combination tablet containing Sacubitril and Valsartan, used in the management of chronic heart failure. Sacubitril is a neprilysin inhibitor, and Valsartan is an angiotensin II receptor blocker (ARB). This combination works by enhancing beneficial neurohormonal systems and suppressing harmful ones, thereby improving heart function and reducing the risk of hospitalization and cardiovascular death in heart failure patients