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Avloclav 625 mg Tablet is indicated for the treatment of infections caused by beta-lactamase-producing bacteria, including upper and lower respiratory tract infections (e.g., sinusitis, pneumonia, bronchitis), urinary tract infections, skin and soft tissue infections, and dental infections.
Avloclav contains Amoxicillin, a semisynthetic penicillin, which inhibits bacterial cell wall synthesis, and Clavulanic Acid, a beta-lactamase inhibitor, which protects Amoxicillin from degradation by beta-lactamase enzymes. This synergy allows the drug to act against a wider spectrum of pathogens.
As prescribed by a registered physician. Standard adult dosage: 1 tablet (625 mg) every 8–12 hours, depending on the severity of the infection.
Take orally at the start of a meal to reduce gastrointestinal side effects and enhance absorption. Swallow the tablet whole with water. Do not crush or chew.
Interactions may occur with allopurinol (increased risk of rash), oral contraceptives (reduced efficacy), methotrexate (increased toxicity), and anticoagulants (increased INR). Probenecid may increase Amoxicillin levels by decreasing renal excretion.
Contraindicated in patients with known hypersensitivity to beta-lactam antibiotics, such as penicillins and cephalosporins. Also contraindicated in patients with previous liver dysfunction or jaundice related to this combination.
Common side effects include nausea, vomiting, diarrhea, skin rash, and abdominal discomfort. Rarely, hepatotoxicity, cholestatic jaundice, or allergic reactions such as anaphylaxis may occur.
Category B — Safe during pregnancy and lactation when clearly needed and under medical supervision.
Use with caution in patients with liver or kidney impairment. Monitor liver function during prolonged use. Discontinue immediately if signs of allergy or liver dysfunction appear.
Penicillins with beta-lactamase inhibitors
Store below 25°C in a dry place. Protect from moisture and light. Keep out of reach of children.