সকল ফার্মেসি পণ্য রংপুর জেলার তামান্না ফার্মেসি থেকে সরবরাহ করা হয়

URSOCOL 300 MG

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Product Code : 121619667700802

Short Description URSOCOL 300 MG contains Ursodeoxycholic Acid, used to dissolve cholesterol gallstones and treat primary biliary cholangitis.
Name Brand Generic Name Strength PPF Price
URSOCOL 300 MG Sun Pharmaceutical (Bangladesh) Ltd. URSODEOXYCHOLIC ACID 300 mg TABLET 25
৳ 25
Qty :

Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:
URSOCOL 300 MG is indicated for:

  • Dissolution of radiolucent cholesterol-rich gallstones in patients with a functioning gallbladder

  • Treatment of primary biliary cholangitis (PBC)

  • Hepatobiliary disorders associated with cystic fibrosis

  • Chronic liver disease with cholestasis

Pharmacology:
Ursodeoxycholic Acid is a naturally occurring bile acid that reduces the cholesterol content of bile by suppressing hepatic synthesis and secretion of cholesterol and by inhibiting its intestinal absorption. It also protects liver cells and improves bile flow, reducing inflammation and fibrosis.

Dosage & Administration:

  • Gallstone dissolution: 8–12 mg/kg/day in divided doses, continued for 6–24 months depending on stone size

  • PBC: 13–15 mg/kg/day in 2–4 divided doses

  • Children (cystic fibrosis-related liver disease): dose individualized based on body weight

  • Administer with food for better absorption

Interaction:

  • Bile acid sequestrants (e.g., cholestyramine) reduce absorption—administer with a gap of 2–4 hours

  • Aluminum-based antacids may reduce absorption

  • Estrogens and oral contraceptives may counteract the effects by increasing cholesterol saturation

Contraindications:

  • Acute inflammation of the gallbladder or biliary tract

  • Complete biliary obstruction

  • Calcified gallstones

  • Hypersensitivity to Ursodeoxycholic Acid

  • Pregnancy (unless clearly necessary)

Side Effects:

  • Diarrhea (most common)

  • Nausea, vomiting, abdominal pain

  • Skin rash, pruritus (rare)

  • Transient elevation of liver enzymes

Pregnancy & Lactation:
Should be used in pregnancy only if clearly necessary and prescribed by a physician. Not recommended during breastfeeding unless the benefit outweighs the risk.

Precautions & Warnings:

  • Liver function should be monitored regularly during therapy

  • Periodic ultrasound to assess gallstone dissolution

  • Discontinue if no reduction in stone size after 12 months

  • Caution in patients with chronic liver disease

Therapeutic Class:
Hepatic protectors / Bile acid therapy

Storage Conditions:
Store below 30°C, in a dry place away from light. Keep out of reach of children.