Description
Arokast 5 mg Chewable Tablet is an antihistamine medication manufactured by Navana Pharmaceuticals Ltd., containing 5 mg of Montelukast Sodium. Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT₁). Cysteinyl leukotrienes (LTC₄, LTD₄, LTE₄) are products of arachidonic acid metabolism and are released from various cells, including mast cells and eosinophils. Cysteinyl leukotrienes and leukotriene receptor occupation have been correlated with the pathophysiology of asthma and allergic rhinitis, including airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of asthma. Arokast 5 mg Chewable Tablet is indicated for the prophylaxis and chronic treatment of asthma, acute prevention of exercise-induced bronchoconstriction (EIB), and relief of symptoms of allergic rhinitis (AR), including seasonal and perennial allergic rhinitis. The recommended dosage is one tablet once daily in the evening, with or without food. It is important to note that Arokast 5 mg Chewable Tablet is not intended for the reversal of acute bronchospasm in asthma attacks. Common side effects may include headache, abdominal pain, and dizziness. Caution is advised when coadministering with certain medications, such as phenytoin, phenobarbital, and rifampicin. Pregnant or breastfeeding women should consult a healthcare provider before use. Store the medication in a cool, dry place, protected from light and moisture, and out of reach of children
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