Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
DIETA 2 mg is indicated for:
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Type 2 Diabetes Mellitus (non-insulin dependent)
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Monotherapy or combined therapy with Metformin or Insulin
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Patients who cannot control blood sugar with diet and exercise alone
Pharmacology:
Glimepiride is a third-generation sulfonylurea that stimulates the release of insulin from functioning pancreatic beta cells. It also enhances the sensitivity of peripheral tissues to insulin, resulting in improved glucose uptake and utilization. It provides long-lasting blood sugar control with a lower risk of hypoglycemia than older sulfonylureas.
Dosage:
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Usual starting dose: 1–2 mg once daily with breakfast
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Dose may be adjusted up to 8 mg per day based on glycemic response
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Elderly or renal-impaired patients may require lower doses
Administration:
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Take once daily with breakfast
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Do not crush or chew the tablet
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Maintain a regular meal pattern
Interaction:
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Increased hypoglycemic effect when combined with NSAIDs, MAOIs, Insulin, and Beta-blockers
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Effect may be reduced with corticosteroids, thiazide diuretics, and oral contraceptives
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Alcohol may potentiate or weaken the blood glucose-lowering effect
Contraindications:
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Type 1 diabetes
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Diabetic ketoacidosis
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Severe hepatic or renal impairment
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Hypersensitivity to Glimepiride or other sulfonylureas
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Pregnancy and lactation
Side Effects:
Common side effects:
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Hypoglycemia
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Headache
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Nausea
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Dizziness
Less common but serious: -
Hepatic dysfunction
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Blood dyscrasias (e.g., thrombocytopenia, leukopenia)
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Allergic skin reactions
Pregnancy & Lactation:
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Contraindicated during pregnancy; use insulin instead
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Not recommended during breastfeeding as Glimepiride may pass into breast milk
Precautions & Warnings:
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Monitor blood glucose regularly
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Educate patients to recognize hypoglycemia symptoms
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Avoid skipping meals
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Use with caution in elderly, malnourished, or renal-impaired patients
Therapeutic Class:
Oral Hypoglycemic Agents
(Sulfonylureas - Third Generation)
Storage Conditions:
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Store in a cool, dry place below 30°C
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Protect from light and moisture
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Keep out of reach of children
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