Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Type 2 Diabetes Mellitus
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As monotherapy or in combination with Metformin or Insulin
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For patients who need blood glucose control beyond diet and exercise
Pharmacology:
Glimepiride belongs to the sulfonylurea class of antidiabetics. It works by stimulating insulin release from pancreatic beta cells and improving insulin sensitivity in peripheral tissues. It provides long-acting glycemic control with a lower risk of hypoglycemia than earlier sulfonylureas.
Dosage:
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Initial dose: 1–2 mg once daily with breakfast
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Dose can be adjusted based on glycemic response (max 8 mg/day)
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Lower doses for elderly or renal-impaired patients
Administration:
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Take once daily with breakfast
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Do not chew or crush
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Consistent meal schedule is recommended
Interaction:
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Enhanced effect with insulin, NSAIDs, and MAOIs
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Reduced effect with corticosteroids, diuretics, and oral contraceptives
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Alcohol may increase risk of hypoglycemia
Contraindications:
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Type 1 diabetes
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Diabetic ketoacidosis
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Severe hepatic or renal dysfunction
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Hypersensitivity to Glimepiride or other sulfonylureas
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Pregnancy and lactation
Side Effects:
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Hypoglycemia
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Nausea
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Headache
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Dizziness
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Allergic skin reactions
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Rare: liver dysfunction, blood cell disorders
Pregnancy & Lactation:
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Not recommended during pregnancy; insulin is preferred
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Avoid during breastfeeding; may pass into breast milk
Precautions & Warnings:
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Regular blood sugar monitoring is essential
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Caution in elderly, malnourished, or renal-impaired patients
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Avoid skipping meals to prevent hypoglycemia
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Educate patient on recognizing low blood sugar symptoms
Therapeutic Class:
Oral Hypoglycemic Agents
(Sulfonylureas – Third Generation)
Storage Conditions:
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Store below 30°C in a dry place
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Protect from light and moisture
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Keep out of reach of children
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