Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
DIETA 1 mg is indicated for:
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Type 2 Diabetes Mellitus (non-insulin dependent)
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As monotherapy or in combination with other antidiabetics (e.g., Metformin, Insulin)
Pharmacology:
Glimepiride is a third-generation sulfonylurea that stimulates insulin secretion from functioning pancreatic beta cells. It also increases insulin sensitivity at peripheral tissues. It has a long duration of action with less risk of hypoglycemia compared to older sulfonylureas.
Dosage:
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Initial dose: 1 mg once daily with breakfast
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May be increased gradually based on blood glucose response (max 8 mg/day)
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Dose adjustment required in elderly and renal impairment
Administration:
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Take orally with breakfast
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Do not skip meals
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Swallow tablet whole with water
Interaction:
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Enhanced effect with NSAIDs, insulin, MAOIs, and beta-blockers
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Reduced effect with corticosteroids, diuretics, and thyroid products
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Alcohol increases risk of hypoglycemia
Contraindications:
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Type 1 diabetes
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Diabetic ketoacidosis
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Severe renal or hepatic dysfunction
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Hypersensitivity to Glimepiride or other sulfonylureas
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Pregnancy and lactation
Side Effects:
Common side effects include:
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Hypoglycemia
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Headache
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Dizziness
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Nausea
Rare but serious: -
Liver dysfunction
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Allergic skin reactions
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Blood disorders (e.g., leukopenia)
Pregnancy & Lactation:
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Contraindicated during pregnancy; insulin is preferred
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Not recommended during lactation due to potential risk to infant
Precautions & Warnings:
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Regularly monitor blood glucose
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Caution in patients with renal or liver impairment
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Educate patient about symptoms of hypoglycemia
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Avoid alcohol
Therapeutic Class:
Oral Hypoglycemic Agents
(Sulfonylureas - Third Generation)
Storage Conditions:
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Store below 30°C
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Keep in a dry place, protected from light
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Keep out of reach of children
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