Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Treatment of active tuberculosis
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Bacterial infections sensitive to Rifampicin
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Used in combination therapy for tuberculosis and other mycobacterial infections
Pharmacology:
HPR (Hydroxypropyl Rifampicin) is a rifamycin antibiotic that inhibits DNA-dependent RNA polymerase in bacterial cells, preventing RNA synthesis and thus bacterial replication and growth. It is bactericidal and widely used in tuberculosis treatment.
Dosage:
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Typical adult dose: 10 mg/kg once daily or as prescribed by physician
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Duration and dosage depend on the type and severity of infection
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Always follow the prescribed regimen strictly
Administration:
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Take orally on an empty stomach for better absorption (1 hour before or 2 hours after meals)
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Swallow whole with water
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Do not skip doses
Interaction:
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Induces liver enzymes; may reduce effectiveness of other drugs like oral contraceptives, warfarin, antiretrovirals
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Caution with other hepatotoxic drugs
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Inform physician about all medications to avoid interactions
Contraindications:
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Hypersensitivity to Rifampicin or rifamycin derivatives
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Severe liver impairment
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History of jaundice or hepatic dysfunction with Rifampicin
Side Effects:
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Hepatotoxicity (monitor liver function)
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Orange discoloration of urine, sweat, tears
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Gastrointestinal upset
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Flu-like symptoms
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Allergic reactions (rare)
Pregnancy & Lactation:
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Use only if clearly needed; benefits outweigh risks
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Consult healthcare provider before use during pregnancy and breastfeeding
Precautions & Warnings:
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Monitor liver function tests regularly
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Avoid alcohol to reduce liver damage risk
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Complete full course to prevent resistance
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Inform doctor if unusual symptoms develop
Therapeutic Class:
Antibiotic — Rifamycin Group
Storage Conditions:
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Store below 30°C in a dry place
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Protect from light and moisture
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Keep out of reach of children
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