রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Rheumatoid arthritis
Osteoarthritis
Ankylosing spondylitis
Acute gouty arthritis
Bursitis and tendinitis
Pain and inflammation due to musculoskeletal disorders
Indomethacin is a potent NSAID that works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, reducing the formation of prostaglandins responsible for inflammation, pain, and fever.
Usual adult dose: 25 mg 2 to 3 times daily
Dose may be increased based on clinical response but should not exceed 200 mg/day
Should be taken with food or milk to reduce gastrointestinal irritation
Capsule should be swallowed whole with water
May interact with anticoagulants (e.g., warfarin), increasing bleeding risk
Can reduce the effectiveness of antihypertensives and diuretics
Increased risk of nephrotoxicity with ACE inhibitors and NSAIDs
Avoid use with other NSAIDs
Hypersensitivity to indomethacin or other NSAIDs
History of peptic ulcer, GI bleeding
Severe heart failure, hepatic or renal impairment
Asthma exacerbated by NSAIDs
During perioperative pain management in CABG surgery
Common: Nausea, vomiting, abdominal pain, headache, dizziness
Serious: GI bleeding, ulceration, hypertension, renal dysfunction
CNS effects: Depression, confusion (especially in elderly)
Pregnancy: Not recommended, especially in the third trimester
Lactation: Excreted in breast milk; use only if clearly needed and under medical advice
Use lowest effective dose for shortest possible duration
Monitor renal and hepatic function in long-term use
Increased cardiovascular risk with long-term/high-dose use
Caution in elderly and those with GI or cardiovascular risk
Non-Steroidal Anti-Inflammatory Drugs (NSAIDs)
Store below 30°C, in a dry place, away from light and moisture. Keep out of reach of children.