Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
DIATROL MR 30 mg is indicated for:
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Management of Type 2 Diabetes Mellitus
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Patients requiring long-acting glycemic control
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Suitable when diet, exercise, and weight reduction alone are not sufficient
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May be combined with other oral antidiabetics or insulin
Pharmacology:
Gliclazide MR is a modified-release form of Gliclazide, a sulfonylurea that stimulates insulin secretion from pancreatic beta cells. It has a prolonged effect, providing consistent blood glucose control throughout the day. Gliclazide also improves endothelial function and may help in reducing microvascular complications in diabetics.
Dosage:
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Starting dose: 30 mg once daily with breakfast
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May be adjusted up to 120 mg daily based on response
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Titration should be done in 30 mg increments
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Dose adjustment required in elderly and renal impairment
Administration:
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Take once daily with breakfast
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Do not crush or chew the tablet
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Maintain a regular meal schedule to avoid hypoglycemia
Interaction:
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May enhance effects of insulin, metformin, beta-blockers, and anticoagulants
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Hypoglycemia risk increases with alcohol, sulfonamides, NSAIDs
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Antagonized by corticosteroids, oral contraceptives, thiazides
Contraindications:
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Type 1 diabetes
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Diabetic ketoacidosis
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Severe hepatic or renal insufficiency
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Known hypersensitivity to sulfonylureas
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Pregnancy and breastfeeding
Side Effects:
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Hypoglycemia
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Headache
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Dizziness
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Gastrointestinal upset
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Rare: allergic skin reactions, liver enzyme elevation, hematological disorders
Pregnancy & Lactation:
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Not recommended during pregnancy
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Insulin should be used instead
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Contraindicated during lactation as it may be excreted in breast milk
Precautions & Warnings:
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Monitor blood glucose regularly
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Caution in elderly patients
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Avoid skipping meals to reduce hypoglycemia risk
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Renal and hepatic function should be monitored
Therapeutic Class:
Oral Hypoglycemic Agents
(Sulfonylureas - Modified Release)
Storage Conditions:
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Store below 30°C in a dry place
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Keep in original packaging to protect from moisture
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Keep out of reach of children
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