Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
-
Type 2 Diabetes Mellitus
-
Can be used alone or in combination with metformin, sulfonylureas, or insulin when diet and exercise alone do not provide adequate glycemic control
Pharmacology:
Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing levels of incretin hormones, which help regulate blood glucose by increasing insulin release and decreasing glucagon secretion in a glucose-dependent manner.
Dosage & Administration:
-
Recommended dose: 5 mg once daily, with or without food
-
No dose adjustment needed for renal or hepatic impairment
-
Can be taken at any time of the day but preferably at the same time each day
Interaction:
-
Risk of hypoglycemia increases when used with sulfonylureas or insulin
-
Co-administration with rifampin (a potent CYP3A4 inducer) may reduce linagliptin exposure
-
Minimal drug-drug interaction due to primarily non-renal excretion
Contraindications:
-
Hypersensitivity to linagliptin or any component of the formulation
-
Type 1 diabetes or for the treatment of diabetic ketoacidosis
Side Effects:
-
Common: Nasopharyngitis, cough, back pain
-
Rare but serious: Hypersensitivity reactions like angioedema, pancreatitis, urticaria, and exfoliative skin conditions
Pregnancy & Lactation:
-
Pregnancy: Use only if clearly needed and prescribed by a doctor
-
Lactation: It is unknown whether linagliptin is excreted in human milk; caution is advised
Precautions & Warnings:
-
Monitor for signs of pancreatitis
-
Not a substitute for insulin in insulin-requiring patients
-
Monitor blood glucose regularly
-
Use caution in patients with a history of pancreatitis
Therapeutic Class:
Dipeptidyl Peptidase-4 (DPP-4) Inhibitors – Oral Antidiabetic Agents
Storage Conditions:
Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
.jpg)
Change Language