Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Gastroesophageal reflux disease (GERD)
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Peptic ulcers (gastric and duodenal ulcers)
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Zollinger-Ellison syndrome (gastric acid hypersecretion)
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Erosive esophagitis
Pharmacology:
Rabeprazole is a proton pump inhibitor (PPI) that suppresses gastric acid secretion by irreversibly inhibiting the H+/K+ ATPase enzyme in the stomach lining, leading to reduced acid production.
Dosage & Administration:
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Typical dose: 20 mg once daily before a meal
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Duration depends on condition; commonly 4 to 8 weeks for ulcer healing
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Can be taken with or without food
Interaction:
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May reduce absorption of drugs requiring acidic environment (e.g., ketoconazole, atazanavir)
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Can increase serum levels of digoxin and warfarin; monitor accordingly
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Avoid concomitant use with rilpivirine-containing products
Contraindications:
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Hypersensitivity to rabeprazole or other PPIs
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Co-administration with rilpivirine
Side Effects:
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Common: Headache, diarrhea, nausea, abdominal pain
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Rare: Vitamin B12 deficiency with long-term use, interstitial nephritis
Pregnancy & Lactation:
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Pregnancy: Use only if clearly needed, consult doctor
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Lactation: Excretion in breast milk unknown; caution advised
Precautions & Warnings:
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Monitor for symptoms of gastric malignancy before and during treatment
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Long-term use may increase risk of fractures and infections like Clostridium difficile
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Avoid abrupt discontinuation to prevent rebound acid hypersecretion
Therapeutic Class:
Proton Pump Inhibitor (PPI)
Storage Conditions:
Store in a cool, dry place below 30°C, protected from light. Keep out of reach of children.
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