Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Pharmacology:
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Contains Metronidazole, a nitroimidazole-class antimicrobial agent with potent activity against anaerobic bacteria and protozoa.
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In extended-release form, it maintains a stable blood concentration, ensuring longer action and better compliance.
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Works by producing toxic metabolites that interfere with DNA synthesis in anaerobic organisms, causing microbial cell death.
Dosage:
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Usual adult dose: 750 mg once or twice daily, as directed by the physician.
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Course duration depends on the infection type, typically 5–10 days.
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Dose adjustment may be required in renal or hepatic impairment.
Administration:
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Take orally with a full glass of water.
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Preferably taken with food to reduce stomach upset.
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Do not crush or chew the tablet to preserve extended-release properties.
Interaction:
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Avoid alcohol during and 48 hours after taking this medicine to prevent disulfiram-like reactions (nausea, flushing, cramps).
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Possible interactions include:
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Warfarin – increased bleeding risk
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Lithium – potential toxicity
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Cimetidine – may raise metronidazole levels
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Phenytoin, Phenobarbital – may reduce efficacy
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Contraindications:
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Known hypersensitivity to Metronidazole or other nitroimidazole derivatives
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CNS diseases like epilepsy or a history of seizures
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Severe hepatic impairment
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