Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Empamet 12.5/500mg is indicated for the treatment of type 2 diabetes mellitus, especially in patients inadequately controlled on metformin alone. It helps improve glycemic control as an adjunct to diet and exercise.
Pharmacology:
Empamet combines empagliflozin, an SGLT2 inhibitor that increases urinary glucose excretion, with metformin, which decreases hepatic glucose production and improves insulin sensitivity, thereby effectively lowering blood glucose.
Dosage:
Typical starting dose is one tablet twice daily with meals. Dosage adjustments depend on patient response and tolerability.
Administration:
Take orally with meals to reduce gastrointestinal side effects. Swallow the tablet whole with water.
Interaction:
May interact with other antidiabetic agents, diuretics, and drugs affecting renal function. Risk of hypoglycemia increases when combined with insulin or sulfonylureas.
Contraindications:
Not suitable for patients with type 1 diabetes, diabetic ketoacidosis, severe renal impairment (eGFR <30 mL/min/1.73m²), metabolic acidosis, or hypersensitivity to empagliflozin or metformin.
Side Effects:
Common side effects include gastrointestinal discomfort, urinary tract infections, increased urination, and hypoglycemia (especially when combined with insulin). Rare cases of lactic acidosis reported.
Pregnancy & Lactation:
Not recommended during pregnancy and breastfeeding. Use only if benefits outweigh risks.
Precautions & Warnings:
Monitor renal function regularly. Use cautiously in elderly patients and those at risk of dehydration or volume depletion.
Therapeutic Class:
Combination of SGLT2 inhibitor and biguanide antidiabetic agents.
Storage Conditions:
Store below 30°C, in a dry place protected from light. Keep out of reach of children.
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