Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
OMECRON 20 mg is indicated for the treatment of:
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Gastric and duodenal ulcers
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NSAID-associated gastric and duodenal ulcers
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Gastroesophageal reflux disease (GERD)
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Acid-related dyspepsia
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Severe ulcerating reflux esophagitis
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Prophylaxis of acid aspiration during general anesthesia
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Zollinger-Ellison syndrome
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Helicobacter pylori-induced peptic ulcer (as part of combination therapy)
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Prevention of stress ulceration
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Treatment of upper gastrointestinal bleeding
Pharmacology:
Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect reduces gastric acidity, promoting ulcer healing and symptom relief in acid-related disorders.
Dosage & Administration:
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Gastric ulcer: 20 mg once daily for 4–8 weeks
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Duodenal ulcer: 20 mg once daily for 2–4 weeks
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GERD: 20 mg once daily for 4 weeks; may extend to 8 weeks if necessary
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Zollinger-Ellison syndrome: Starting dose of 60 mg daily; dosage adjusted based on patient response
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NSAID-associated ulcers: 20 mg once daily for 4 weeks; for prophylaxis, 20 mg once daily
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H. pylori eradication: 20 mg twice daily in combination with appropriate antibiotics for 7–14 days
Note: Dosage may vary based on individual patient needs and should be determined by a healthcare professional.
Interaction:
Omeprazole may interact with:
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Clopidogrel: May reduce the antiplatelet effect; caution advised
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Warfarin: May increase anticoagulant effect; monitor INR levels
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Diazepam, Phenytoin, and other drugs metabolized by CYP2C19: May increase plasma concentrations
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Methotrexate: High-dose methotrexate therapy may lead to elevated levels; temporary withdrawal of Omeprazole may be considered
Always consult with a healthcare provider before combining medications.
Contraindications:
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Known hypersensitivity to Omeprazole or any component of the formulation
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Concomitant use with products containing rilpivirine
Side Effects:
Common side effects include:
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Headache
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Nausea
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Diarrhea
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Abdominal pain
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Flatulence
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Vomiting
Serious but rare side effects:
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Clostridium difficile-associated diarrhea
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Bone fracture risk with long-term use
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Vitamin B12 deficiency with prolonged use
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Hypomagnesemia
Pregnancy & Lactation:
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Pregnancy: Category C. Should be used during pregnancy only if clearly needed and prescribed by a healthcare provider
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Lactation: Omeprazole is excreted in breast milk; caution is advised
Precautions & Warnings:
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Long-term therapy may lead to atrophic gastritis
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Monitor for signs of gastrointestinal infections
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Use the lowest effective dose for the shortest duration appropriate to the condition being treated
Therapeutic Class:
Proton Pump Inhibitors (PPIs)
Storage Conditions:
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.
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