Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Acute bacterial sinusitis
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Community-acquired pneumonia
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Pharyngitis and tonsillitis
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Skin and soft tissue infections
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Urethritis and cervicitis caused by Chlamydia trachomatis
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Otitis media
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Mycobacterium avium complex (MAC) infections
Pharmacology:
Azithromycin is a macrolide antibiotic that binds to the 50S ribosomal subunit of susceptible microorganisms and inhibits protein synthesis, thereby preventing bacterial growth.
Dosage & Administration:
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Adults: 500 mg once daily for 3 days (or 500 mg on day 1 followed by 250 mg once daily for the next 4 days)
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Can be taken with or without food
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Capsule should be swallowed whole with water
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Full course must be completed even if symptoms improve earlier
Interaction:
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Antacids (especially aluminum/magnesium) can reduce absorption
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Increased risk of arrhythmias with QT-prolonging drugs
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May enhance effects of warfarin, digoxin, and cyclosporine
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Avoid concomitant use with ergot derivatives
Contraindications:
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Hypersensitivity to azithromycin, erythromycin, or other macrolides
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History of cholestatic jaundice/hepatic dysfunction associated with prior azithromycin use
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Severe hepatic impairment
Side Effects:
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Common: Nausea, vomiting, abdominal discomfort, diarrhea
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Less common: Headache, dizziness, skin rash
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Rare: QT prolongation, hepatotoxicity, severe allergic reactions
Pregnancy & Lactation:
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Pregnancy: Category B – use only if clearly needed
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Lactation: Excreted in breast milk; monitor infant for GI disturbances
Precautions & Warnings:
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Caution in patients with heart rhythm disorders (especially QT prolongation)
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Hepatic function should be monitored during prolonged therapy
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Discontinue immediately if severe allergic reaction occurs
Therapeutic Class:
Macrolide antibiotic
Storage Conditions:
Store below 30°C in a dry, cool place. Protect from light and moisture. Keep out of reach of children.
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