Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Ludiomil 25 mg is indicated for:
-
Treatment of depressive disorders, especially those associated with anxiety
-
Endogenous depression
-
Neurotic depression
-
Dysthymia and other chronic mood disorders
Pharmacology:
Ludiomil contains Maprotiline, a tetracyclic antidepressant. It inhibits the reuptake of norepinephrine and, to a lesser extent, serotonin, thereby increasing their levels in the central nervous system. This results in mood elevation and anxiety reduction.
Dosage & Administration:
-
Adults: Initial dose is 25–75 mg per day; maintenance dose ranges from 75–150 mg per day, usually in divided doses or as a single dose at night.
-
Elderly: Lower initial dose (25 mg), adjusted cautiously based on response.
-
Not recommended for use in children unless directed by a specialist.
Interaction:
-
Risk of CNS depression increases when used with alcohol, sedatives, or other CNS depressants.
-
Should not be used with MAO inhibitors due to risk of serious interactions.
-
May interact with SSRIs, increasing the risk of serotonin syndrome.
-
May enhance effects of anticholinergic and sympathomimetic drugs.
Contraindications:
-
Hypersensitivity to Maprotiline or other tricyclic antidepressants
-
Recent myocardial infarction
-
Seizure disorders
-
Severe liver or kidney impairment
-
Use with monoamine oxidase inhibitors (MAOIs)
Side Effects:
-
Common: Dry mouth, drowsiness, dizziness, constipation, blurred vision
-
Less common: Weight gain, urinary retention, low blood pressure
-
Rare: Seizures, cardiac arrhythmias, blood disorders
Pregnancy & Lactation:
-
Pregnancy: Should be used only if clearly needed; potential risk to fetus exists
-
Lactation: Maprotiline may pass into breast milk; not recommended unless advised by a doctor
Precautions & Warnings:
-
Increased risk of suicidal thoughts, especially in young adults
-
Use cautiously in patients with heart disease, glaucoma, or seizure history
-
Avoid abrupt discontinuation—taper dose gradually
-
Periodic liver function and blood count monitoring may be necessary during prolonged use
Therapeutic Class:
Tetracyclic (Tricyclic-like) Antidepressants
Storage Conditions:
Store below 30°C in a dry, cool place away from direct sunlight. Keep out of reach of children.
Change Language