Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Treatment of essential hypertension
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Suitable for patients requiring combination therapy for blood pressure control
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May be prescribed alone or with other antihypertensive agents
Pharmacology:
Exforge combines two agents:
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Amlodipine: A calcium channel blocker that dilates blood vessels and reduces vascular resistance.
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Valsartan: An angiotensin II receptor blocker (ARB) that inhibits vasoconstriction and lowers blood pressure.
Their combined action helps achieve effective and sustained blood pressure control.
Dosage & Administration:
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Usually one tablet once daily, with or without food
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Dose adjustment based on therapeutic response and tolerability
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Not recommended in severe hepatic or renal impairment without specialist advice
Interaction:
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Increased risk of hypotension with other antihypertensives
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Potential hyperkalemia with potassium supplements or potassium-sparing diuretics
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Caution with NSAIDs, lithium, and other nephrotoxic drugs
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Avoid combination with ACE inhibitors due to risk of renal impairment
Contraindications:
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Hypersensitivity to amlodipine, valsartan, or excipients
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Pregnancy and breastfeeding
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Severe liver dysfunction or biliary obstruction
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Severe renal impairment without monitoring
Side Effects:
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Common: Edema, dizziness, headache, fatigue
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Less common: Palpitations, flushing, abdominal discomfort
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Rare: Angioedema, hypotension, elevated liver enzymes
Pregnancy & Lactation:
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Pregnancy: Contraindicated; may cause fetal harm
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Lactation: Not recommended
Precautions & Warnings:
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Regular monitoring of blood pressure, renal and liver function advised
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Use cautiously in patients with heart failure or volume depletion
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Avoid abrupt discontinuation; taper doses if necessary
Therapeutic Class:
Antihypertensive – Calcium Channel Blocker + Angiotensin II Receptor Blocker
Storage Conditions:
Store in a cool, dry place below 30°C, away from direct sunlight. Keep out of reach of children.
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