Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Neptor 20 mg is indicated for the treatment of gastroesophageal reflux disease (GERD), peptic ulcers, erosive esophagitis, Helicobacter pylori eradication therapy, and Zollinger-Ellison syndrome.
Pharmacology:
Neptor contains Esomeprazole, the S-isomer of omeprazole, a proton pump inhibitor. It inhibits gastric acid secretion by blocking the H+/K+ ATPase enzyme system in gastric parietal cells. Esomeprazole provides longer-lasting acid suppression compared to omeprazole.
Dosage & Administration:
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Adults: Typically 20 mg once daily before meals.
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The dose may vary depending on the condition.
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In H. pylori eradication, it is used in combination with antibiotics.
Interaction:
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May affect absorption of drugs where gastric pH is important (e.g., ketoconazole, atazanavir).
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May increase levels of diazepam, warfarin, and phenytoin.
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Reduced effectiveness of clopidogrel when taken together.
Contraindications:
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Known hypersensitivity to esomeprazole, other substituted benzimidazoles, or any component of the formulation.
Side Effects:
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Common: Headache, diarrhea, nausea, abdominal pain, flatulence
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Rare: Dry mouth, dizziness, allergic reactions, low magnesium with long-term use
Pregnancy & Lactation:
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Pregnancy: Esomeprazole is considered relatively safe during pregnancy when clearly needed.
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Lactation: Use with caution as it may be excreted in breast milk.
Precautions & Warnings:
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Long-term therapy may lead to vitamin B12 deficiency, osteoporosis-related fractures, or hypomagnesemia.
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Rule out malignancy if used to treat gastric symptoms.
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Use cautiously in patients with severe liver impairment.
Therapeutic Class:
Proton Pump Inhibitors (PPI)
Storage Conditions:
Store below 25°C, in a dry place protected from light and moisture. Keep out of reach of children.
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