Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Treatment of anaerobic bacterial infections
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Treatment of protozoal infections such as amoebiasis and trichomoniasis
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Used for infections of the gastrointestinal tract, genitourinary tract, skin, and respiratory tract
Pharmacology:
Metronidazole is an antibiotic and antiprotozoal agent. It enters microbial cells and causes DNA strand breakage, inhibiting nucleic acid synthesis, resulting in cell death of anaerobic bacteria and protozoa.
Dosage & Administration:
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Typical adult dose: 500 mg orally every 8-12 hours depending on infection severity
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Duration depends on infection type and response to therapy
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Should be taken with food to minimize gastrointestinal upset
Interaction:
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Alcohol consumption must be avoided during therapy and for 48 hours after due to disulfiram-like reaction
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May increase effects of warfarin and lithium
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Possible interaction with phenytoin, phenobarbital, and cyclosporine
Contraindications:
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Hypersensitivity to metronidazole or related compounds
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First trimester of pregnancy (use only if clearly necessary)
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Use caution in patients with severe liver impairment
Side Effects:
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Common: Nausea, metallic taste, headache, dizziness
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Less common: Abdominal cramps, diarrhea, rash
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Rare: Neurotoxicity (peripheral neuropathy), seizures
Pregnancy & Lactation:
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Pregnancy: Avoid in the first trimester unless benefit outweighs risk
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Lactation: Use with caution as metronidazole passes into breast milk
Precautions & Warnings:
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Avoid alcohol during and 48 hours post-treatment
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Monitor neurological symptoms during prolonged use
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Use with caution in patients with liver dysfunction
Therapeutic Class:
Antibiotic / Antiprotozoal
Storage Conditions:
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
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