Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Treatment of essential hypertension
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For patients needing combination therapy to achieve blood pressure control
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Can be used alone or with other antihypertensive agents
Pharmacology:
Exforge contains:
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Amlodipine: A calcium channel blocker that relaxes vascular smooth muscle, lowering peripheral resistance and blood pressure.
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Valsartan: An angiotensin II receptor blocker that prevents vasoconstriction, reducing blood pressure.
The combination provides complementary mechanisms to manage hypertension effectively.
Dosage & Administration:
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One tablet daily, with or without food
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Dose adjustments should be based on clinical response
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Not recommended for severe hepatic or renal impairment without medical supervision
Interaction:
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May cause hypotension when combined with other antihypertensives
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Increased potassium levels with potassium-sparing diuretics or supplements
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Caution with NSAIDs, lithium, and drugs affecting renal function
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Avoid concurrent use with ACE inhibitors
Contraindications:
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Hypersensitivity to components
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Pregnancy and breastfeeding
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Severe hepatic impairment or biliary obstruction
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Severe renal impairment without monitoring
Side Effects:
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Common: Peripheral edema, dizziness, headache, fatigue
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Less common: Palpitations, flushing, abdominal discomfort
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Rare: Angioedema, hypotension, liver enzyme abnormalities
Pregnancy & Lactation:
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Pregnancy: Contraindicated due to potential fetal risk
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Lactation: Not recommended
Precautions & Warnings:
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Monitor blood pressure and renal/liver function regularly
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Use caution in heart failure or volume depletion patients
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Do not stop medication abruptly
Therapeutic Class:
Antihypertensive – Calcium Channel Blocker + Angiotensin II Receptor Blocker
Storage Conditions:
Store below 30°C in a dry place, protected from light. Keep out of reach of children.
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