Anadol Plus is a combination analgesic tablet produced by Square Pharmaceuticals PLC, containing Paracetamol 325 mg and Tramadol Hydrochloride 37.5 mg. This medication is formulated to manage moderate to moderately severe pain in adults. It is particularly effective for short-term (five days or less) treatment of acute pain. Paracetamol acts centrally to alleviate pain and reduce fever, while Tramadol, a centrally acting synthetic opioid analgesic, binds to μ-opioid receptors and inhibits the reuptake of norepinephrine and serotonin, enhancing its analgesic effects.