Bisocor® Plus 5 mg/6.25 mg Tablet is a combination medication manufactured by Square Pharmaceuticals Ltd., designed for the effective management of hypertension (high blood pressure). Each tablet contains 5 mg of Bisoprolol Fumarate, a selective β1-adrenergic receptor blocker, and 6.25 mg of Hydrochlorothiazide, a thiazide diuretic. This combination works synergistically to lower blood pressure by reducing heart rate and cardiac output (via Bisoprolol) and by promoting the excretion of excess sodium and water (via Hydrochlorothiazide), thereby decreasing blood volume and vascular resistance.