Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
SECRIN 2 MG is indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus, when diet, exercise, and weight reduction alone are not adequate.
Pharmacology:
Glimepiride is a second-generation sulfonylurea that stimulates insulin release from pancreatic beta cells. It also increases the sensitivity of peripheral tissues to insulin and reduces hepatic glucose production.
Dosage & Administration:
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Usual starting dose is 1 to 2 mg once daily with breakfast or the first main meal.
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Dose may be adjusted based on blood glucose response up to a maximum of 8 mg per day.
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Titration should occur at 1 to 2 week intervals based on blood glucose monitoring.
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Do not skip meals after taking the medication.
Interaction:
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Increased hypoglycemic effect with NSAIDs, insulin, other antidiabetics, ACE inhibitors, and alcohol.
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Reduced effect with corticosteroids, thiazides, and sympathomimetics.
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Beta-blockers may mask symptoms of hypoglycemia.
Contraindications:
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Type 1 diabetes mellitus
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Diabetic ketoacidosis
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Severe renal or hepatic impairment
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Hypersensitivity to Glimepiride or other sulfonylureas/sulfonamides
Side Effects:
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Hypoglycemia (most common)
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Dizziness, headache
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Nausea, weight gain
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Rare: Allergic skin reactions, hepatic dysfunction
Pregnancy & Lactation:
Contraindicated in pregnancy. Use insulin instead. Glimepiride may pass into breast milk; breastfeeding is not recommended during therapy.
Precautions & Warnings:
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Risk of hypoglycemia—ensure proper meal intake
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Monitor blood glucose regularly
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Use with caution in elderly or patients with adrenal/pituitary insufficiency
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Avoid alcohol consumption
Therapeutic Class:
Sulfonylurea group of oral hypoglycemic agents
Storage Conditions:
Store in a dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
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