Ucol 2 mg Tablet

Ucol 2 mg Tablet

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Product Code : 121419666100501

Short Description Antimuscarinic tablet for overactive bladder—reduces urinary urgency, frequency, and urge incontinence.

Name	Brand	Generic Name	Strength	PPF	Price
Ucol 2 mg Tablet	SQUARE PHARMACEUTICALS LTD	TOLTERODINE TARTRATE	2 mg	TABLET	5

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Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:
Treatment of overactive bladder symptoms: urinary urgency, frequency, and urge incontinence.

Pharmacology:
Tolterodine is a competitive muscarinic receptor antagonist with high selectivity for bladder smooth muscle over salivary glands. Its active metabolite (5‑hydroxymethyl derivative) contributes to the therapeutic effect, typically manifesting within 4 weeks.

Dosage:

Adults: Standard dose is 2 mg twice daily.
If side effects occur, reduce to 1 mg twice daily.
For those with liver/renal impairment or taking potent CYP3A4 inhibitors, limit to 2 mg per day (1 mg b.i.d.).
Re-evaluate use after 6 months.

Administration:
Oral use; swallow whole (do not crush or chew), with or without food.

Interaction:

Potent CYP3A4 inhibitors (e.g., ketoconazole, erythromycin, clarithromycin, itraconazole, ritonavir, cyclosporine, vinblastine) increase Tolterodine levels—adjust dosing accordingly.
No significant interactions with warfarin or hormonal contraceptives.
Caution with QT-prolonging drugs (e.g., Class I A/III antiarrhythmics).
Avoid alcohol—can worsen drowsiness.

Contraindications:
Urinary retention, gastric retention, uncontrolled narrow-angle glaucoma, hypersensitivity to Tolterodine.

Side Effects:
Dry mouth (23–40%), headache, constipation, blurred vision, dizziness, dry eyes, urinary retention, abdominal discomfort.

Pregnancy & Lactation:
Use only if benefits justify risks. No human data—avoid during breastfeeding.

Precautions & Warnings:
Use cautiously in patients with bladder outflow obstruction, GI motility disorders, hepatic or renal impairment, glaucoma, and those taking QT-prolonging drugs. Monitor for drowsiness, blurred vision.

Therapeutic Class:
BPH / Urinary retention / Urinary incontinence (muscarinic receptor antagonist)

Storage Conditions:
Store in a cool, dry place below 30 °C, protect from light, and keep out of children’s reach.