Hydroxyethyl Starch 130/0.4 is a colloidal plasma volume substitute used intravenously to treat and prevent hypovolemia, a condition characterized by low blood volume. It is commonly administered in clinical settings such as surgeries, trauma care, or severe burns to restore circulating blood volume and maintain blood pressure. Volulyte 6% combines 6% hydroxyethyl starch with a balanced electrolyte solution, including sodium chloride, sodium acetate, potassium chloride, and magnesium chloride. This formulation helps to reduce the risk of hyperchloremic metabolic acidosis—a common issue with saline-based solutions—by providing a more balanced electrolyte profile. The solution is designed for intravenous infusion and should be administered under medical supervision, with careful monitoring of kidney function, coagulation parameters, and fluid balance.