Furosemide is a potent loop diuretic that works by inhibiting the reabsorption of sodium and chloride in the kidneys, leading to increased urine production. It is commonly used to manage conditions such as edema (fluid retention) due to heart failure, liver disease, or kidney disorders. Spironolactone, on the other hand, is a potassium-sparing diuretic that helps the body retain potassium while promoting the excretion of excess sodium and water. It is typically prescribed for managing high blood pressure, heart failure, and certain hormonal imbalances like hyperaldosteronism. Together, these medications help reduce fluid buildup, control blood pressure, and improve overall cardiovascular health by addressing fluid retention and electrolyte imbalances.