Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Zero 8 mg is indicated for the short-term treatment of insomnia characterized by difficulties with sleep initiation.
Pharmacology:
Zolpidem is a non-benzodiazepine sedative-hypnotic acting on the GABA-A receptor complex, enhancing inhibitory neurotransmission and producing sedation and hypnosis.
Dosage & Administration:
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Adults: 5 to 10 mg immediately before bedtime.
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Use lowest effective dose; 8 mg typical for adult men.
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Avoid use for more than 2–4 weeks due to risk of dependence.
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Take orally with a full glass of water; ensure 7–8 hours of sleep time.
Interaction:
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Enhanced sedative effects with CNS depressants, alcohol, benzodiazepines, opioids.
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Caution with drugs metabolized by CYP3A4 (e.g., ketoconazole, rifampin).
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Avoid concomitant use with other hypnotics unless advised by physician.
Contraindications:
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Hypersensitivity to Zolpidem
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Severe hepatic impairment
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Respiratory depression or sleep apnea syndrome
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History of substance abuse
Side Effects:
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Drowsiness, dizziness, headache
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Gastrointestinal upset
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Memory disturbances, complex sleep behaviors (sleepwalking)
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Rare: Allergic reactions, mood changes
Pregnancy & Lactation:
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Use only if benefits outweigh risks.
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Not recommended during breastfeeding.
Precautions & Warnings:
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Risk of dependence and withdrawal symptoms
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Use caution in elderly and those with psychiatric disorders
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Avoid driving or operating machinery after use
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Taper dose gradually if discontinuing
Therapeutic Class:
Sedative-Hypnotics (Non-benzodiazepine)
Storage Conditions:
Store below 25°C in a dry place away from light. Keep out of reach of children.
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