JANMET 1000 is a combination medication used primarily in the treatment of Type 2 diabetes mellitus. It contains two active ingredients: Metformin Hydrochloride and Vildagliptin. Metformin is a biguanide that works by improving the body’s sensitivity to insulin, helping to control blood sugar levels. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that enhances insulin release when blood sugar levels are high, and also reduces the amount of glucose produced by the liver. This combination therapy helps regulate blood glucose levels, improve insulin function, and may reduce the risk of complications associated with diabetes, when used alongside diet and exercise.