Description
Limbix 12.5 mg + 5 mg tablet, manufactured by ACME Laboratories Ltd., is a combination medication used to treat moderate to severe depression associated with moderate to severe anxiety. Each tablet contains 12.5 mg of Amitriptyline Hydrochloride and 5 mg of Chlordiazepoxide. Amitriptyline is a tricyclic antidepressant that works by inhibiting the reuptake of norepinephrine and serotonin in the brain, thereby enhancing mood and alleviating depressive symptoms. Chlordiazepoxide is a benzodiazepine that acts as an anxiolytic by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA), leading to sedation and reduced anxiety. This combination is particularly effective for patients experiencing both depression and anxiety symptoms such as insomnia, feelings of guilt or worthlessness, agitation, and suicidal ideation. The typical dosage involves taking 3 to 4 tablets daily in divided doses, with the larger portion taken at bedtime. However, the dosage may vary based on individual patient needs and should be determined by a healthcare provider. Common side effects include drowsiness, dry mouth, constipation, blurred vision, dizziness, and bloating. It is contraindicated in patients with hypersensitivity to either benzodiazepines or tricyclic antidepressants and should not be used concomitantly with monoamine oxidase inhibitors (MAOIs). Caution is advised in patients with a history of seizures, thyroid disorders, or impaired liver or kidney function. As with all medications, it is essential to follow the prescribing healthcare professional's instructions and to monitor for any adverse reactions
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