Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Lino is indicated for:
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Type 2 diabetes mellitus in adults to improve blood sugar control
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As monotherapy or in combination with metformin, sulfonylureas, or insulin
Pharmacology:
Linagliptin is a DPP-4 (dipeptidyl peptidase-4) inhibitor. It increases incretin hormone levels (GLP-1 and GIP), which enhance insulin secretion and suppress glucagon secretion in a glucose-dependent manner, thereby reducing blood glucose levels without causing hypoglycemia.
Dosage & Administration:
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Usual dose: 5 mg once daily
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Can be taken with or without food
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No dose adjustment needed in renal or hepatic impairment
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Take at the same time each day for best results
Interaction:
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May enhance hypoglycemia when used with sulfonylureas or insulin
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Rifampin may reduce the efficacy of Linagliptin
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Minimal interaction with other commonly used antidiabetics
Contraindications:
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Hypersensitivity to Linagliptin or any component of the formulation
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Not recommended for type 1 diabetes or diabetic ketoacidosis
Side Effects:
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Common: Nasopharyngitis, cough, headache
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Less common: Hypoglycemia (especially when combined with insulin), back pain
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Rare: Pancreatitis, hypersensitivity reactions
Pregnancy & Lactation:
Use only if clearly needed and prescribed by a physician. Safety in pregnancy and lactation not well established.
Precautions & Warnings:
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Not a substitute for insulin in insulin-dependent patients
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Monitor blood sugar levels regularly
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Discontinue if pancreatitis is suspected
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Use with caution in patients with a history of pancreatitis
Therapeutic Class:
DPP-4 (Dipeptidyl Peptidase-4) Inhibitor
Storage Conditions:
Store below 30°C in a cool, dry place away from sunlight and moisture. Keep out of reach of children.
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