Lino-M 1000 mg is a combination medication used for the management of type 2 diabetes mellitus. It contains Linagliptin (2.5 mg), a Dipeptidyl Peptidase-4 (DPP-4) inhibitor, and Metformin Hydrochloride (1000 mg), a biguanide. Linagliptin works by increasing the levels of incretin hormones, which stimulate insulin release and reduce glucose production in the liver. This helps lower blood sugar levels, particularly after meals. Metformin works by reducing liver glucose production, improving insulin sensitivity, and decreasing glucose absorption in the intestines. Together, these two medications help control blood glucose levels in individuals with type 2 diabetes, especially when diet and exercise alone are insufficient. The typical dosage of Lino-M 1000 mg is 1 tablet twice daily with meals. This combination can help reduce the risk of complications related to diabetes by improving overall blood sugar control.