Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
FOLIX is indicated for:
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Treatment and prevention of megaloblastic anemia due to folic acid deficiency
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Prevention of neural tube defects in pregnancy
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Folate deficiency in malnutrition, alcoholism, liver disease
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Supportive treatment in patients receiving methotrexate or phenytoin
Pharmacology:
Folic acid (Vitamin B9) is a water-soluble B-vitamin essential for nucleoprotein synthesis and maintenance of normal erythropoiesis (red blood cell formation). It is converted into tetrahydrofolate, which is vital for DNA and RNA synthesis.
Dosage & Administration:
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Adults (Anemia or Deficiency): 5 mg once daily or as directed
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Pregnancy (Prevention of Neural Tube Defects): Usually 400 mcg–5 mg daily, starting before conception through the first trimester
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Can be taken with or without food
Interaction:
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May interact with methotrexate, trimethoprim, and certain anticonvulsants (e.g., phenytoin)
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Zinc absorption may be reduced with long-term use
Contraindications:
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Hypersensitivity to folic acid
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Undiagnosed anemia without proper investigation (e.g., pernicious anemia)
Side Effects:
Generally well tolerated. Rarely:
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Gastrointestinal discomfort (nausea, bloating)
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Allergic reactions (rash, itching)
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Sleep disturbances with high doses
Pregnancy & Lactation:
Safe and recommended during pregnancy and breastfeeding under medical supervision.
Precautions & Warnings:
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Should not be used to treat anemia of unknown cause
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High doses may mask vitamin B12 deficiency, leading to neurological damage
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Regular monitoring recommended in long-term therapy
Therapeutic Class:
Hematinics (Vitamins & Minerals – Folic Acid)
Storage Conditions:
Store below 30°C in a dry, cool place. Protect from light and moisture. Keep out of reach of children.
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