Description
Flunarizine is a selective calcium channel antagonist primarily used for the prophylactic treatment of migraines, including both classical (with aura) and common (without aura) types. It is also effective in managing vestibular vertigo, peripheral vascular disease, motion sickness, and as an adjunct in refractory epilepsy. Flunarizine functions by reducing excessive calcium influx into cells, thereby preventing cellular calcium overload and stabilizing neuronal activity. Additionally, it possesses antihistaminic and sedative properties. Common side effects include drowsiness, fatigue, weight gain, and increased appetite. Patients should be cautious when engaging in activities requiring mental alertness, such as driving, due to potential sedation. The safety of flunarizine during pregnancy and lactation has not been established, and it is contraindicated in individuals with a history of depressive illness or extrapyramidal disorders. It is essential to consult a healthcare provider before initiating treatment with flunarizine to ensure its appropriateness for the individual's health condition.
.jpeg)
.webp)
.png)
.jpeg)
.jpeg)
.png)
.webp)
.webp)
.png)
Change Language