Description
Pilestop is a phlebotonic and vascular-protecting agent manufactured by ACME Laboratories Ltd. It combines Micronised Diosmin (450 mg) and Hesperidin (50 mg), both flavonoid compounds known for their beneficial effects on venous circulation.
Indications:
-
Acute hemorrhoidal attacks
-
Chronic hemorrhoidal disease
-
Chronic venous insufficiency (CVI)
-
Lymphedema
Mechanism of Action:
Pilestop enhances venous tone by prolonging the vasoconstrictor effect of noradrenaline on the vessel wall, reducing venous stasis. It also decreases capillary permeability and increases capillary resistance by inhibiting leukocyte adhesion, migration, and activation. Additionally, it improves lymphatic drainage by increasing lymph flow and oncotic pressure.
Dosage & Administration:
-
Acute hemorrhoidal attacks:
-
First 4 days: 3 tablets twice daily
-
Next 3 days: 2 tablets twice daily
-
Maintenance (if required): 1 tablet twice daily for approximately 2 months
-
-
Chronic hemorrhoidal disease: 1 tablet twice daily for 2–3 months
-
Chronic venous insufficiency: 1 tablet twice daily for 2 months
-
Lymphedema: 1 tablet twice daily for 6 months
Note: Tablets should be taken with meals.
Side Effects:
Some patients may experience minor gastrointestinal disturbances or autonomic disorders; however, these rarely necessitate discontinuation of therapy.
Precautions:
-
Use during pregnancy: Animal studies have not demonstrated teratogenic effects, and no harmful effects have been reported in humans to date.
-
Use during lactation: In the absence of data on excretion into breast milk, breastfeeding is not recommended during treatment.
Storage:
-
Store in a cool, dry place protected from light.
-
Keep out of reach of children.
Availability:
Pilestop is available in blister packs containing 2 x 10 tablets.
.jpeg)
.webp)
.jpeg)
.jpeg)
.webp)
.png)
.webp)
.png)
.png)
Change Language