FENOLID 200MG

FENOLID 200MG

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Product Code : 107710710501301

Short Description

Fenolid is a 200 mg capsule used to lower high cholesterol and triglyceride levels in the blood, thereby reducing the risk of cardiovascular diseases.

Name	Brand	Generic Name	Strength	PPF	Price
FENOLID 200MG	General Pharmaceuticals Ltd.	FENOFIBRATE	200MG	Capsule	7

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Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।

Indications:

Fenolid is indicated for the treatment of:

Hypercholesterolemia (type IIa, IIb)
Mixed hyperlipidemia (type III)
Hypertriglyceridemia (type IV, V)

It is used in patients who have not responded adequately to diet and other appropriate measures.

Pharmacology:

Fenolid contains fenofibrate, a fibric acid derivative. It is rapidly hydrolyzed to its active form, fenofibric acid, which activates peroxisome proliferator-activated receptor alpha (PPARα). This activation leads to increased lipoprotein lipase activity and decreased secretion of apolipoprotein C-III, resulting in enhanced clearance of triglyceride-rich lipoproteins from the bloodstream. Additionally, fenofibrate increases HDL cholesterol levels by increasing the synthesis of apolipoproteins AI and AII.

Dosage & Administration:

Adults with hypercholesterolemia or mixed hyperlipidemia: The initial dose is 200 mg once daily.
Adults with hypertriglyceridemia: The initial dose is between 67 to 200 mg per day.
Fenolid should be taken with food to enhance absorption.

Interaction:

Warfarin: Fenolid may potentiate the anticoagulant effects of warfarin.
Antidiabetic drugs: May improve glucose tolerance and have an additive effect.
Cyclosporine: May increase nephrotoxicity.
Statins: Caution is advised due to potential increased risk of rhabdomyolysis; however, low-dose statins with Fenolid appear to be well tolerated.

Contraindications:

Hypersensitivity to fenofibrate or any of its components.
Severe renal impairment.
Severe hepatic impairment.
Gallbladder disease.
Breastfeeding.

Side Effects:

Common: Diarrhea, stomach pain, nausea, vomiting, flatulence, elevated liver enzymes.
Uncommon: Headache, gallstones, reduced sex drive, rash, itching, increased creatinine levels.
Serious (rare): Muscle pain, weakness, or cramps (myopathy), pancreatitis, blood clots (deep vein thrombosis or pulmonary embolism), liver inflammation (hepatitis), allergic reactions.

Pregnancy & Lactation:

Pregnancy: Fenolid should only be used during pregnancy after a careful benefit/risk assessment.
Lactation: It is unknown whether fenofibrate and/or its metabolites are excreted in human milk. A risk to the suckling child cannot be excluded. Therefore, fenofibrate should not be used during breastfeeding.